IBS-C
Resources
Understanding and managing IBS-C can be a lot. Here you can find tools that may help.
Downloadable tools FOR IBSRELA
IBS-Check-in Tool
Don’t be okay with feeling just okay. If you continue to have IBS-C symptoms that bother you, you are not alone. Answer these questions about your IBS-C symptoms to start a conversation with your healthcare provider to see if IBSRELA is right for you.
Get to know IBSRELA
Detailed information about IBSRELA.
Conoce sobre IBSRELA
Información detallada sobre IBSRELA.
Pay as little as $0*
for IBSRELA
Eligible patients with commercial insurance pay as little as $0* per 30-day prescription fill of IBSRELA. The discount will be automatically applied for eligible patients at the majority of pharmacies.
*Please see terms and conditions.
Need help getting IBSRELA?
ArdelyxAssist™ is here to help.
Call us at 844-427-7352, option 1
if you have any questions or need support with IBSRELA access or affordability.
View transcript
Title Screen with IBSRELA Indication and Boxed Warning
ON SCREEN/SUPER: Suzanne
Retired nurse, patient with IBS-C
Suzanne VO:
Hi my name is Suzanne. I’m a retired nurse from Michigan. I’m here today to tell you a little bit about my experience living with Irritable Bowel Syndrome with Constipation, or IBS-C. I’m joined by Susan, my nurse practitioner who works with me to manage my IBS-C, and whom I can’t say enough wonderful things about. Susan has been my savior, and I feel very fortunate to have her. She understands me and my condition – and has been committed to working with me to find the IBS-C treatment that works for me.
IBS-C very much impacted my ability to live my life. I used to go 14-15 days without a bowel movement – and I had terrible cramping and bloating. I remember my clothes were so tight. I love to go camping with my husband – and now that we are retired, we have plenty of time to do so. But I never wanted to leave the house just in case I got the urge to go to the bathroom. And the abdominal pain and bloating were so bad – I really didn’t feel like doing much of anything.
I took an over-the-counter medication for a while but it didn’t work for me. I would still go a week or more without a bowel movement – and still had terrible abdominal pain and bloating. I tried a prescription medication for IBS-C – but it didn’t work for me either. Before I saw Susan, I was feeling discouraged.
Video transitions to Susan
ON SCREEN/SUPER: Susan Wolgamott, DNP
Susan is a compensated advisor to Ardelyx
Susan VO:
Hi, my name is Susan. I am a nurse practitioner in Michigan. I have so many patients like Suzanne, who are suffering because of their IBS-C. I think as healthcare providers, we sometimes forget the impact that conditions like IBS-C have on our patients. This is not just a nuisance disorder – it is a condition that can have a very negative impact on patients’ quality of life.
Because there are many potential underlying causes of IBS-C, there is no one-size fits all treatment approach. It’s a lot of trial and error to find the right medication for each individual patient. It’s important that patients understand that. That’s why I let my patients know that we have different medications to treat IBS-C.
I also talk to my patients about the importance of good two-way communication, because this is a collaborative, joint decision-making process. I make sure my patients know that we will work together to find the treatment that is right for each of them.
And there’s nothing more satisfying than finding the right treatment for a patient. For Suzanne, it was IBSRELA, which works differently than other IBS-C prescription medications. And I think that if a patient is on a medication that isn’t working for them or giving them symptom relief they are looking for, it makes sense to try something different. While IBSRELA was right for Suzanne, some patients experience side effects with IBSRELA, like diarrhea, swelling or a feeling of fullness in the abdomen, gas, or dizziness.
ON SCREEN/SUPER: The most common side effects of IBSRELA include diarrhea, swelling or a feeling of fullness in the abdomen, gas, or dizziness.
Suzanne VO:
Since starting IBSRELA about a year ago, my symptoms have improved. I no longer feel the bloating or pain like I did before. I go to the bathroom more regularly, which I haven’t been able to do in many years. This has been my experience with IBSRELA and other people may have different experiences. Because my symptoms are better managed, I am able to go camping with my husband and spend time with my grandkids. My husband and I both lost our first spouses early – we know that life is short. We want to be able to do the things that bring us joy. I am so grateful that Susan was committed to helping me find a treatment that was right for me.
ON SCREEN/SUPER: Individual results and experiences may vary.
Susan VO:
It gives me joy to help patients like Suzanne. I think the key is good communication between patients and healthcare providers. I feel it is my responsibility to let my patients know that there are different options available, and to offer them different treatment options.
When I suggested trying IBSRELA to Suzanne, I didn’t know if it was going to work for her, but she and I agreed that it would be worth trying. And I am so glad we did!
Important Safety Information, including Boxed Warning (Patient ISI)
†Individual results and experiences may vary.
‡Susan is a compensated advisor to Ardelyx.
The IBS-Connection
Hear from Patients who have had success with symptom relief on IBSRELA
Watch Suzanne talk about finding the medication that’s right for her and her IBS-C,† with the help of her trusted healthcare provider, Susan.‡
†Individual results and experiences may vary.
‡Susan is a compensated advisor to Ardelyx.
View transcript
Title Screen with IBSRELA Indication and Boxed Warning
ON SCREEN/SUPER: Suzanne
Retired nurse, patient with IBS-C
Suzanne VO:
Hi my name is Suzanne. I’m a retired nurse from Michigan. I’m here today to tell you a little bit about my experience living with Irritable Bowel Syndrome with Constipation, or IBS-C. I’m joined by Susan, my nurse practitioner who works with me to manage my IBS-C, and whom I can’t say enough wonderful things about. Susan has been my savior, and I feel very fortunate to have her. She understands me and my condition – and has been committed to working with me to find the IBS-C treatment that works for me.
IBS-C very much impacted my ability to live my life. I used to go 14-15 days without a bowel movement – and I had terrible cramping and bloating. I remember my clothes were so tight. I love to go camping with my husband – and now that we are retired, we have plenty of time to do so. But I never wanted to leave the house just in case I got the urge to go to the bathroom. And the abdominal pain and bloating were so bad – I really didn’t feel like doing much of anything.
I took an over-the-counter medication for a while but it didn’t work for me. I would still go a week or more without a bowel movement – and still had terrible abdominal pain and bloating. I tried a prescription medication for IBS-C – but it didn’t work for me either. Before I saw Susan, I was feeling discouraged.
Video transitions to Susan
ON SCREEN/SUPER: Susan Wolgamott, DNP
Susan is a compensated advisor to Ardelyx
Susan VO:
Hi, my name is Susan. I am a nurse practitioner in Michigan. I have so many patients like Suzanne, who are suffering because of their IBS-C. I think as healthcare providers, we sometimes forget the impact that conditions like IBS-C have on our patients. This is not just a nuisance disorder – it is a condition that can have a very negative impact on patients’ quality of life.
Because there are many potential underlying causes of IBS-C, there is no one-size fits all treatment approach. It’s a lot of trial and error to find the right medication for each individual patient. It’s important that patients understand that. That’s why I let my patients know that we have different medications to treat IBS-C.
I also talk to my patients about the importance of good two-way communication, because this is a collaborative, joint decision-making process. I make sure my patients know that we will work together to find the treatment that is right for each of them.
And there’s nothing more satisfying than finding the right treatment for a patient. For Suzanne, it was IBSRELA, which works differently than other IBS-C prescription medications. And I think that if a patient is on a medication that isn’t working for them or giving them symptom relief they are looking for, it makes sense to try something different. While IBSRELA was right for Suzanne, some patients experience side effects with IBSRELA, like diarrhea, swelling or a feeling of fullness in the abdomen, gas, or dizziness.
ON SCREEN/SUPER: The most common side effects of IBSRELA include diarrhea, swelling or a feeling of fullness in the abdomen, gas, or dizziness.
Suzanne VO:
Since starting IBSRELA about a year ago, my symptoms have improved. I no longer feel the bloating or pain like I did before. I go to the bathroom more regularly, which I haven’t been able to do in many years. This has been my experience with IBSRELA and other people may have different experiences. Because my symptoms are better managed, I am able to go camping with my husband and spend time with my grandkids. My husband and I both lost our first spouses early – we know that life is short. We want to be able to do the things that bring us joy. I am so grateful that Susan was committed to helping me find a treatment that was right for me.
ON SCREEN/SUPER: Individual results and experiences may vary.
Susan VO:
It gives me joy to help patients like Suzanne. I think the key is good communication between patients and healthcare providers. I feel it is my responsibility to let my patients know that there are different options available, and to offer them different treatment options.
When I suggested trying IBSRELA to Suzanne, I didn’t know if it was going to work for her, but she and I agreed that it would be worth trying. And I am so glad we did!
Important Safety Information, including Boxed Warning (Patient ISI)
IBS-C online communities and resources
Check out the available IBS-C resources and communities
Frequently asked questions
About IBS-C
About IBSRELA
How to get IBSRELA
What is IBS-C, and what does IBS-C stand for?
IBS-C, or irritable bowel syndrome with constipation, is a common condition. People with IBS-C experience constipation, belly pain, bloating, and discomfort.
What are common IBS-C symptoms?
Constipation symptoms of IBS-C may include
- Infrequent bowel movements (fewer than 3 per week)
- Hard or lumpy stools
- Straining to go to the bathroom
- Feeling that your bowels do not empty completely
Belly symptoms of IBS-C may include
- Pain
- Bloating
- Discomfort
What causes IBS-C?
There are many possible and different causes of IBS-C:
- Slow stool movement (or slow motility)—When stool moves through the gut too slowly
- Leaky gut (or increased intestinal permeability)—When the gut allows more than just water and nutrients (such as unwanted particles or toxins) through the intestinal barrier and into the bloodstream
- Sensitive nerves (or visceral hypersensitivity)—When the nerves in the intestines are extra sensitive, normal stimuli may cause increased belly pain
- Gut-brain interaction—The gut and brain talk to each other, so changes in one can cause changes in the other
What is IBSRELA?
IBSRELA is a prescription medication for adults with irritable bowel syndrome with constipation (IBS-C) that works differently to relieve the constipation, belly pain, and bloating of IBS-C.
What is the most important information I should know about IBSRELA?
- Do not give IBSRELA to children who are less than 6 years of age. It may harm them.
- You should not give IBSRELA to patients 6 years to less than 18 years of age. It may harm them. IBSRELA can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
See “What are the possible side effects of IBSRELA?” for more information about side effects.
Who should not take IBSRELA?
- Do not give IBSRELA to children who are less than 6 years of age. IBSRELA can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
- Do not take IBSRELA if a doctor has told you that you have a bowel blockage (intestinal obstruction).
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.
How is IBSRELA different from other IBS-C prescription medications?
IBSRELA works in a different way than other IBS-C medications.
IBSRELA relieves the symptoms of IBS-C by:
- Keeping water in the gut to help soften stool and help it move along, so you have more well-formed and regular bowel movements
- Restoring gut barrier function* to reduce belly pain
- Lessening the activity of pain-sensing nerves in the intestine* to reduce belly pain
IBSRELA works exclusively in the intestine to help reduce, improve, and relieve the symptoms of IBS-C.
*This was seen in animal studies, and the relevance to humans is not known.
Who is IBSRELA for?
IBSRELA is a prescription medicine used in adults to treat IBS-C. It is not known if IBSRELA is safe and effective in children less than 18 years of age.
What symptoms does IBSRELA help with?
- Constipation—People treated with IBSRELA experienced more bowel movements per week, with a feeling of complete emptying
- Belly pain—With IBSRELA, improvement in belly pain is typically felt within one week, and many people felt even more improvement as treatment continued*
- Bloating—Bloating is typically improved within one week of starting IBSRELA, and improvements usually continue as treatment continued*
*Improvement seen through end of 26-week trial.
How many times a day do I need to take IBSRELA?
IBSRELA is a 50-mg tablet taken twice a day, just before breakfast and just before dinner.
When should I take IBSRELA if I do not eat breakfast?
If you don’t eat breakfast, take IBSRELA immediately before your first meal of the day and immediately prior to dinner.
What if I forget to take my IBSRELA?
If you miss a dose, skip the missed dose, and take the next dose at the regular time. Do not take 2 doses of IBSRELA at the same time.
What are the common side effects of IBSRELA?
IBSRELA can cause serious side effects, including:
- See “What is the most important information I should know about IBSRELA?”
- Diarrhea is the most common side effect of IBSRELA, and it can sometimes be severe. Stop taking IBSRELA and call your doctor if you develop severe diarrhea.
The other most common side effects of IBSRELA include:
- swelling, or a feeling of fullness or pressure in your abdomen (distension).
- gas (flatulence).
- dizziness
These are not all the possible side effects of IBSRELA. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to www.fda.gov/medwatch.
What is the IBSRELA Copay Savings Program?
Patients with commercial coverage may pay as little as $0* per prescription through the IBSRELA copay program.
*Terms and conditions apply.
Do I need a physical Copay Card to participate in the Savings program?
No, a physical copay card is not needed to get the savings. Eligible patients can participate in the Copay Savings program without having to show a physical Copay Savings Card.
How do I get a prescription for IBSRELA?
Your healthcare provider can give you a prescription for IBSRELA.
What can I do if I have trouble getting IBSRELA?
ArdelyxAssist™ is here to help. Call us at 844-427-7352, option 1 if you have any questions or need support with IBSRELA access or affordability.
Frequently asked questions
About IBS-C
What is IBS-C, and what does IBS-C stand for?
IBS-C, or irritable bowel syndrome with constipation, is a common condition. People with IBS-C experience constipation, belly pain, bloating, and discomfort.
What are common IBS-C symptoms?
Constipation symptoms of IBS-C may include
- Infrequent bowel movements (fewer than 3 per week)
- Hard or lumpy stools
- Straining to go to the bathroom
- Feeling that your bowels do not empty completely
Belly symptoms of IBS-C may include
- Pain
- Bloating
- Discomfort
What causes IBS-C?
There are many possible and different causes of IBS-C:
- Slow stool movement (or slow motility)—When stool moves through the gut too slowly
- Leaky gut (or increased intestinal permeability)—When the gut allows more than just water and nutrients (such as unwanted particles or toxins) through the intestinal barrier and into the bloodstream
- Sensitive nerves (or visceral hypersensitivity)—When the nerves in the intestines are extra sensitive, normal stimuli may cause increased belly pain
- Gut-brain interaction—The gut and brain talk to each other, so changes in one can cause changes in the other
About IBSRELA
What is IBSRELA?
IBSRELA is a prescription medication for adults with irritable bowel syndrome with constipation (IBS-C) that works differently to relieve the constipation, belly pain, and bloating of IBS-C.
What is the most important information I should know about IBSRELA?
- Do not give IBSRELA to children who are less than 6 years of age. It may harm them.
- You should not give IBSRELA to patients 6 years to less than 18 years of age. It may harm them. IBSRELA can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
See “What are the possible side effects of IBSRELA?” for more information about side effects.
Who should not take IBSRELA?
- Do not give IBSRELA to children who are less than 6 years of age. IBSRELA can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
- Do not take IBSRELA if a doctor has told you that you have a bowel blockage (intestinal obstruction).
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.
How is IBSRELA different from other IBS-C prescription medications?
IBSRELA works in a different way than other IBS-C medications.
IBSRELA relieves the symptoms of IBS-C by:
- Keeping water in the gut to help soften stool and help it move along, so you have more well-formed and regular bowel movements
- Restoring gut barrier function* to reduce belly pain
- Lessening the activity of pain-sensing nerves in the intestine* to reduce belly pain
IBSRELA works exclusively in the intestine to help reduce, improve, and relieve the symptoms of IBS-C.
*This was seen in animal studies, and the relevance to humans is not known.
Who is IBSRELA for?
IBSRELA is a prescription medicine used in adults to treat IBS-C. It is not known if IBSRELA is safe and effective in children less than 18 years of age.
What symptoms does IBSRELA help with?
- Constipation—People treated with IBSRELA experienced more bowel movements per week, with a feeling of complete emptying
- Belly pain—With IBSRELA, improvement in belly pain is typically felt within one week, and many people felt even more improvement as treatment continued*
- Bloating—Bloating is typically improved within one week of starting IBSRELA, and improvements usually continue as treatment continued*
*Improvement seen through end of 26-week trial.
How many times a day do I need to take IBSRELA?
IBSRELA is a 50-mg tablet taken twice a day, just before breakfast and just before dinner.
When should I take IBSRELA if I do not eat breakfast?
If you don’t eat breakfast, take IBSRELA immediately before your first meal of the day and immediately prior to dinner.
What if I forget to take my IBSRELA?
If you miss a dose, skip the missed dose, and take the next dose at the regular time. Do not take 2 doses of IBSRELA at the same time.
What are the common side effects of IBSRELA?
IBSRELA can cause serious side effects, including:
- See “What is the most important information I should know about IBSRELA?”
- Diarrhea is the most common side effect of IBSRELA, and it can sometimes be severe. Stop taking IBSRELA and call your doctor if you develop severe diarrhea.
The other most common side effects of IBSRELA include:
- swelling, or a feeling of fullness or pressure in your abdomen (distension).
- gas (flatulence).
- dizziness
These are not all the possible side effects of IBSRELA. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to www.fda.gov/medwatch.
How to get IBSRELA
What is the IBSRELA Copay Savings Program?
Patients with commercial coverage may pay as little as $0* per prescription through the IBSRELA copay program.
*Terms and conditions apply.
Do I need a physical Copay Card to participate in the Savings program?
No, a physical copay card is not needed to get the savings. Eligible patients can participate in the Copay Savings program without having to show a physical Copay Savings Card.
How do I get a prescription for IBSRELA?
Your healthcare provider can give you a prescription for IBSRELA.
What can I do if I have trouble getting IBSRELA?
ArdelyxAssist™ is here to help. Call us at 844-427-7352, option 1 if you have any questions or need support with IBSRELA access or affordability.
IMPORTANT RISK INFORMATION
- Do not give IBSRELA to children who are less than 6 years of age. It may harm them.
- You should not give IBSRELA to patients 6 years to less than 18 years of age. It may harm them. IBSRELA can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
- Do not take IBSRELA if a doctor has told you that you have a bowel blockage (intestinal obstruction).
Before you take IBSRELA, tell your doctor about your medical conditions, including if you are:
- Pregnant or plan to become pregnant. It is not known if IBSRELA will harm your unborn baby.
- Breastfeeding or plan to breastfeed. It is not known if IBSRELA passes into your breast milk. Talk with your doctor about the best way to feed your baby if you take IBSRELA.
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.
Side Effects
Diarrhea is the most common side effect of IBSRELA, and it can sometimes be severe. Stop taking IBSRELA and call your doctor if you develop severe diarrhea.
Other common side effects of IBSRELA include swelling, or a feeling of fullness or pressure in your abdomen (distension), gas (flatulence), or dizziness.
These are not all the possible side effects of IBSRELA. Call your doctor for medical advice about side effects.
What is IBSRELA?
IBSRELA (tenapanor) is a prescription medicine used in adults to treat irritable bowel syndrome with constipation (IBS-C). It is not known if IBSRELA is safe and effective in children less than 18 years of age.
You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to www.fda.gov/medwatch.
Please also see Medication Guide within the full Prescribing Information.
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IMPORTANT RISK INFORMATION
- Do not give IBSRELA to children who are less than 6 years of age. It may harm them.
- You should not give IBSRELA to patients 6 years to less than 18 years of age. It may harm them. IBSRELA can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
- Do not take IBSRELA if a doctor has told you that you have a bowel blockage (intestinal obstruction).
Before you take IBSRELA, tell your doctor about your medical conditions, including if you are:
- Pregnant or plan to become pregnant. It is not known if IBSRELA will harm your unborn baby.
- Breastfeeding or plan to breastfeed. It is not known if IBSRELA passes into your breast milk. Talk with your doctor about the best way to feed your baby if you take IBSRELA.
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.
Side Effects
Diarrhea is the most common side effect of IBSRELA, and it can sometimes be severe. Stop taking IBSRELA and call your doctor if you develop severe diarrhea.
Other common side effects of IBSRELA include swelling, or a feeling of fullness or pressure in your abdomen (distension), gas (flatulence), or dizziness.
These are not all the possible side effects of IBSRELA. Call your doctor for medical advice about side effects.
What is IBSRELA?
IBSRELA (tenapanor) is a prescription medicine used in adults to treat irritable bowel syndrome with constipation (IBS-C). It is not known if IBSRELA is safe and effective in children less than 18 years of age.
You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to www.fda.gov/medwatch.
Please also see Medication Guide within the full Prescribing Information.