ABOUT IBSRELA
IBSRELA works differently to relieve the symptoms of IBS‑C...so that you can focus on what’s important to you
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Could IBSRELA be the difference for you?

Click on each symptom to see how IBSRELA can help.
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Constipation

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People treated with IBSRELA experienced more bowel movements per week, with a feeling of complete emptying

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Belly pain

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With IBSRELA, improvement in belly pain is typically felt within one week. Many people felt even more improvement as treatment continued*

*Improvement seen through end of 26-week trial.

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Bloating

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Bloating is typically improved within one week of starting IBSRELA. Improvements usually continue as treatment is continued*

*Improvement seen through end of 26-week trial.

Ask your healthcare provider if IBSRELA could be the right medication for you.
Regina

THE IBS-CONNECTION

The Confidence to Travel Again

Regina’s painful IBS‑C symptoms used to keep her at home, and away from friends and family. With IBSRELA helping to control her IBS-C symptoms, Regina had the confidence to take a trip abroad with her daughter. Hear her story.†

Watch the full video.

†Individual results and experiences may vary.

Regina is an actual patient taking IBSRELA and has been compensated for discussing her experience.

View transcript

ON SCREEN/SUPER: On Regina’s IBS‑C symptom relief with IBSRELA

Disclaimer: Regina’s experiences are specific to her. Individual experiences and results may vary.

Safety Disclaimer: The most common side effects of IBSRELA include diarrhea, swelling or a feeling of fullness in the abdomen, gas, or dizziness.

Regina VO:

When my doctor and I first started talking about IBSRELA, she told me it was different than the other medications I have already tried. That's a big reason why I was so excited to take IBSRELA….Before starting IBSRELA my doctor and I had talked about the possible side effects, one of which was loose stool. This isn't the only side effect and some patients may experience others. It's important that patients talk to their healthcare providers about all the possible side effects…Now that I’m taking IBSRELA and it relieves my symptoms…I can now make plans and go out with my husband and my friends. I'm able to travel and I recently went to Italy with my daughter. Other people may have different experiences with IBSRELA, but I feel like I've gained some of my life back.

My trip to Italy with my daughter was very important….Me being on IBSRELA to relieve the symptoms of my IBS‑C made it so that I didn't have to miss out…I could go and visit, I could go to Florence, I could do the tours, I could go to the Leaning Tower of Pisa with her. Uh, we went on the cruise, we visited all the places. We took all the tours. I was able to have cocktails with her and just spend really good quality time with her.

THE FAST FACTS

IBSRELA provides quick and lasting relief‡ of IBS‑C symptoms
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Most people taking IBSRELA begin to experience relief from constipation, bloating, belly pain, and discomfort within one week of treatment
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Additional improvement in abdominal pain happens over the first 3-4 months of treatment
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Improvements in IBS‑C symptoms are typically maintained with continued use of IBSRELA‡

‡Improvement seen through end of 26-week trial.

IBSRELA provides relief from IBS‑C symptoms, so you can get back to doing what you enjoy.
Whether that means making plans. Or making up reasons not to make plans!
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What are the common side effects of IBSRELA?

Diarrhea is the most common side effect experienced by those taking IBSRELA

If diarrhea occurs with IBSRELA, it tends to be mild-to-moderate and typically goes away within one week

Stop taking IBSRELA and call your healthcare provider if you experience severe diarrhea while taking IBSRELA

Other common side effects of IBSRELA may include

swelling, or a feeling of fullness or pressure in your belly, gas, and dizziness

Suzanne

THE IBS-CONNECTION

From Missing Out to “Count Me In.”

With IBSRELA, Suzanne’s IBS‑C symptoms are better managed so that she can get back to doing things that bring her joy.§

Hear how IBSRELA helps Suzanne manage her IBS‑C symptoms.

Watch the full video.

§Individual results and experiences may vary.

Suzanne is an actual patient taking IBSRELA and has been compensated for discussing her experience.

View transcript

ON SCREEN/SUPER: Suzanne
Retired nurse, living with IBS‑C

Suzanne VO:

Since starting IBSRELA about a year ago, I go to the bathroom more regularly, which I haven’t been able to do in many years.

For me IBSRELA has made a difference in my symptoms. I no longer feel bloating and pain like I did before. Because my symptoms are better managed, I am able to go camping with my husband and spend time with my grandkids.

ON SCREEN/SUPER: Individual results and experiences may vary.

While this has been my personal experience with IBSRELA, other people may experience some side effects such as diarrhea, swelling or a feeling of fullness in the abdomen, gas, or dizziness.

HOW DOES IBSRELA WORK?

IBSRELA works in a different way than other IBS‑C medications.
IBSRELA relieves the symptoms of IBS‑C by:
Keeping water in the gut to soften stool and help it move along
Keeping water in the gut to help soften stool and help it move along, so you have more well-formed and regular bowel movements.
Restoring gut barrier function
Restoring gut barrier function|| to reduce belly pain.
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Lessening the activity of pain-sensing nerves in the intestine|| to reduce belly pain.

||This was seen in animal studies, and the relevance to humans is not known.

IBSRELA works exclusively in the intestine to help reduce, improve, and relieve the symptoms of IBS‑C.
Woman stretching on yoga mat
Getting started with IBSRELA

IMPORTANT RISK INFORMATION

  • Do not give IBSRELA to children who are less than 6 years of age. It may harm them.
  • You should not give IBSRELA to patients 6 years to less than 18 years of age. It may harm them. IBSRELA can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • Do not take IBSRELA if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take IBSRELA, tell your doctor about your medical conditions, including if you are:

  • Pregnant or plan to become pregnant. It is not known if IBSRELA will harm your unborn baby.
  • Breastfeeding or plan to breastfeed. It is not known if IBSRELA passes into your breast milk. Talk with your doctor about the best way to feed your baby if you take IBSRELA.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Side Effects

Diarrhea is the most common side effect of IBSRELA, and it can sometimes be severe. Stop taking IBSRELA and call your doctor if you develop severe diarrhea.

Other common side effects of IBSRELA include swelling, or a feeling of fullness or pressure in your abdomen (distension), gas (flatulence), or dizziness.

These are not all the possible side effects of IBSRELA. Call your doctor for medical advice about side effects.

You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to www.fda.gov/medwatch.

What is IBSRELA?

IBSRELA (tenapanor) is a prescription medicine used in adults to treat irritable bowel syndrome with constipation (IBS-C). It is not known if IBSRELA is safe and effective in children less than 18 years of age.

Please also see Medication Guide within the full Prescribing Information.

IMPORTANT RISK INFORMATION

  • Do not give IBSRELA to children who are less than 6 years of age. It may harm them.
  • You should not give IBSRELA to patients 6 years to less than 18 years of age. It may harm them. IBSRELA can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • Do not take IBSRELA if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take IBSRELA, tell your doctor about your medical conditions, including if you are:

  • Pregnant or plan to become pregnant. It is not known if IBSRELA will harm your unborn baby.
  • Breastfeeding or plan to breastfeed. It is not known if IBSRELA passes into your breast milk. Talk with your doctor about the best way to feed your baby if you take IBSRELA.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Side Effects

Diarrhea is the most common side effect of IBSRELA, and it can sometimes be severe. Stop taking IBSRELA and call your doctor if you develop severe diarrhea.

Other common side effects of IBSRELA include swelling, or a feeling of fullness or pressure in your abdomen (distension), gas (flatulence), or dizziness.

These are not all the possible side effects of IBSRELA. Call your doctor for medical advice about side effects.

You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to www.fda.gov/medwatch.

What is IBSRELA?

IBSRELA (tenapanor) is a prescription medicine used in adults to treat irritable bowel syndrome with constipation (IBS-C). It is not known if IBSRELA is safe and effective in children less than 18 years of age.

Please also see Medication Guide within the full Prescribing Information.