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IBSRELA: A DIFFERENT KIND OF MEDICATION TO TREAT IBS‑C

IBSRELA is a prescription medicine that works in three ways to treat irritable bowel syndrome with constipation (IBS‑C) in adults

See how IBSRELA works differently from other medications for IBS‑C

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Many people with IBS‑C feel frustrated and stressed about their condition

In a survey of more than 1300 people with IBS‑C, half reported their symptoms as very/extremely bothersome, and as having a negative impact on their productivity and personal activities

And despite treatment, more than three-quarters of those people continued to experience belly pain and/or constipation

Could you benefit from a different approach to treat your IBS‑C?

Could you benefit from

WHY IBSRELA?

IBSRELA works differently from other medications for IBS‑C.

a different approach to treat your IBS‑C?

IBSRELA can:

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Help you have more well-formed and regular bowel movements

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Improve your belly pain, including bloating, discomfort, cramping, and fullness

IBSRELA can:

calendar icon

Help you have more well-formed and regular bowel movements

gut icon

Improve your belly pain, including bloating, discomfort, cramping, and fullness

IBSRELA works in three ways to treat the constipation and pain of IBS‑C

1

SOFTENS STOOL AND ACCELERATES BOWEL MOVEMENTS TO IMPROVE CONSTIPATION

2

IMPROVES LEAKY GUT* TO REDUCE ABDOMINAL PAIN

1

SOFTENS STOOL AND ACCELERATES BOWEL MOVEMENTS TO IMPROVE CONSTIPATION

3

LESSENS THE ACTIVITY OF PAIN-SENSING NERVES IN THE INTESTINE* TO REDUCE ABDOMINAL PAIN

*
This was seen in animal studies, and the relevance to humans is not known.

IBSRELA is an oral medication

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a pill that is taken twice a day, just before breakfast and just before dinner

WHAT ARE THE POSSIBLE SIDE EFFECTS?

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WHAT ARE THE POSSIBLE SIDE EFFECTS?

  • The most common side effect of IBSRELA is diarrhea
  • In clinical trials, for those who experienced diarrhea, it tended to be:
    • Mild-to-moderate
    • Typically went away with continued treatment (in ≤1 week)
  • Stop taking IBSRELA and call your doctor if you experience severe diarrhea while taking IBSRELA
  • In addition to diarrhea, the other most common side effects are:
    • Swelling, or a feeling of fullness or pressure in your abdomen (distension)
    • Gas (flatulence)
    • Dizziness

IT’S IMPORTANT TO TALK WITH YOUR DOCTOR ABOUT YOUR EXPERIENCE WITH IBSRELA

  • These are not all the possible side effects of IBSRELA. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to www.fda.gov/medwatch
  • Keep IBSRELA and all medicines out of the reach of children
  • Do not take IBSRELA if you have been told by your doctor that you have a bowel blockage (intestinal obstruction)

PAY AS LITTLE AS $0 FOR COMMERCIALLY INSURED PATIENTS

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Patients with commercial insurance can pay as little as $0† per prescription through the IBSRELA copay program

† Terms and conditions apply.

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ArdelyxAssist™ is here to help. Call us at 844-427-7352, option 1 if you have any questions or need support with IBSRELA access or affordability.

IMPORTANT RISK INFORMATION
  • Do not give IBSRELA to children who are less than 6 years of age. It may harm them.
  • You should not give IBSRELA to patients 6 years to less than 18 years of age. It may harm them. IBSRELA can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • Do not take IBSRELA if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take IBSRELA, tell your doctor about all your medical conditions, including if you are:

  • Pregnant or plan to become pregnant. It is not known if IBSRELA will harm your unborn baby.
  • Breastfeeding or plan to breastfeed. It is not known if IBSRELA passes into your breast milk. Talk with your doctor about the best way to feed your baby if you take IBSRELA.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Side Effects

Diarrhea is the most common side effect of IBSRELA, and it can sometimes be severe. Stop taking IBSRELA and call your doctor if you develop severe diarrhea.

Other common side effects of IBSRELA include swelling, or a feeling of fullness or pressure in your abdomen (distension), gas (flatulence), or dizziness.

These are not all the possible side effects of IBSRELA. Call your doctor for medical advice about side effects.

What is IBSRELA?

IBSRELA (tenapanor) is a prescription medicine used in adults to treat irritable bowel syndrome with constipation (IBS-C). It is not known if IBSRELA is safe and effective in children less than 18 years of age.

You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to www.fda.gov/medwatch.

Please also see Medication Guide within the full Prescribing Information.

IMPORTANT RISK INFORMATION
  • Do not give IBSRELA to children who are less than 6 years of age. It may harm them.
  • You should not give IBSRELA to patients 6 years to less than 18 years of age. It may harm them. IBSRELA can cause severe diarrhea and your child could get severe dehydration (loss of a large amount of body water and salt).
  • Do not take IBSRELA if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take IBSRELA, tell your doctor about all your medical conditions, including if you are:

  • Pregnant or plan to become pregnant. It is not known if IBSRELA will harm your unborn baby.
  • Breastfeeding or plan to breastfeed. It is not known if IBSRELA passes into your breast milk. Talk with your doctor about the best way to feed your baby if you take IBSRELA.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Side Effects

Diarrhea is the most common side effect of IBSRELA, and it can sometimes be severe. Stop taking IBSRELA and call your doctor if you develop severe diarrhea.

Other common side effects of IBSRELA include swelling, or a feeling of fullness or pressure in your abdomen (distension), gas (flatulence), or dizziness.

These are not all the possible side effects of IBSRELA. Call your doctor for medical advice about side effects.

What is IBSRELA?

IBSRELA (tenapanor) is a prescription medicine used in adults to treat irritable bowel syndrome with constipation (IBS-C). It is not known if IBSRELA is safe and effective in children less than 18 years of age.

You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to www.fda.gov/medwatch.

Please also see Medication Guide within the full Prescribing Information.